William G. Clarke, Canadian born surgeon, was educated in England and matriculated from Cavendish College, Cambridge, in 1883. Continuing his studies at Downing College, University of Cambridge, he obtained the degree Bachelor of Arts (BA) with second class honours in the Natural Science Tripos, Part 1, in 1886 and the degree Master of Arts (MA) in 1890. He was a deeply religious person and served for some years as schoolmaster at Skipton (in Yorkshire) and Cranleigh (in Surrey). After training at St. Bartholomew's Hospital in London and at the University of London he qualified as a Member of the Royal College of Surgeons of England and a Licentiate of the Royal College of Physicians of London in 1895. Two years later he became a Fellow of the Royal College of Surgeons. He was a Fellow also of the Royal Medical and Chirurgical Society, and the author of papers on "Ectoptic gestation cases of caesarian section", etc. After working as house surgeon, obstetric assistant, and demonstrator of physiology at St. Bartholomew's School and Hospital he practised for a short time in London. In 1899 he volunteered to take part in the Anglo-Boer War (1899-1902) as a civil surgeon and upon his return to England settled briefly in Chester.
In 1902 Clark moved to Rhodesia (now Zimbabwe) and settled in Bulawayo. He became resident surgeon at Memorial Hospital, medical officer of health to Buluwayo Municipality, director of the Rhodesian Pasteur Institute, and medical officer to the Rhodesian Labour Bureau. In 1904 he published a paper in The Lancet on 'The Memorial Hospital, Bulawayo: (1) A case of interscapulo-thoracic amputation; and (2) a case of caesarean section'. He built up a good practice and was in partnership with J.H.D. Acland.
Clark became a member of the Rhodesia Scientific Association in 1902 and served on its council in 1903/4. At a meeting of the Association on 25 March 1903 he read a paper on "Rabies: Its history, its cause, and its treatment", which was published in the Proceedings (Vol. 4, pp. 5-10). He was still a member in 1906, and still living in Bulawayo at the time if his death in 1916.