Otto Moszeik, a German physician, studied medicine at Koenigsberg (now Kaliningrad, Russia) and qualified as a medical practitioner by passing the German Staats Examen in 1887. His dissertation dealt with his microscopic morphological investigations of glycogen deposits in the liver of frogs. The dissertation was published in the form of a 38 page monograph (in German) in 1887, and a lengthy paper in the Archiv fuer die gesammte Physiologie des Menschen und der Tiere, in 1888. In 1885 he had already published a paper on the influence of temperature on the absorption ability of animal charcoal, in the Archiv fuer Anatomie und Physiologie, Physiologische Abtheilung.
Moszeik later came to the Cape Colony, where he was licensed to practice medicine on 24 December 1900, and settled in the Barkley East district. In 1905 he published a comprehensive, illustrated paper on South African rock art (in German) in the Internationales Archiv fuer Ethnographie. The text was subsequently revised and augmented and published as a book, Die Malereien der Buschmaenner in Suedafrika (Berlin, 1910), with 173 illustrations. By 1907 he was residing at Moshesh's Ford, a ford in the Kraai River some 20 km north-east of Barkley East. In 1911 he published a paper on the preventive treatment of tuberculosis in the Deutsche Medizinische Wochenschrift (1911).