George Melvill was the son of Samuel Melvill* and his wife Martha Henrietta Amelia Ahrens, and a brother of the surveyor Edward H.V. Melvill*. He became a member of the Chemical and Metallurgical Society of South Africa (from 1902 the Chemical, Metallurgical and Mining Society of South Africa) in 1895. By 1905 he was employed as cyanide manager at the Henry Nourse Gold Mining Company in Johannesburg. In November 1908 he contributed "A few notes on cupelling gold-lead bullion", which was published in the Journal of the Chemical, Metallurgical and Mining Society of South Africa (Vol. 9, p. 157).
There was a G. Melville who studied at the South African College during 1888 only, who may be the same person. Melvill was survived by his wife, Mildred Stella Melvill, born Baker, and three children.