Luise (also Louise) F.C. Leipoldt was the eldest child of Christiaan Friedrich Leipoldt, a Rhenish missionary on Sumatra at the time of her birth, and his wife Anna M.C. Leipoldt, born Esselen. Two of her brothers were the well-known author and poet C.F. Louis Leipoldt*, and the surveyor J.G.W. Leipoldt*. The family came to South Africa and settled in Worcester before she was five years old. She became a teacher and married Robert John Stephen Pattison in Cape Town on 28 June 1900. They had four children.
Miss L. Leipoldt, presumably her, presented zoological specimens collected near George to the South African Museum, Cape Town, during 1899. The specimens included 15 spiders and one Solifuga that were new to the museum's collections. There were also two small mammals in spirit, a snake, a frog, and a number of scorpions.