William Frances (or Francis) Schlupp, American entomologist, was the son of Alexander Schlupp and his wife Samantha J. Browning. He was awarded the degree Bachelor of Science (BSc) by Ohio State University. In 1914 he came to South Africa, where he lectured in zoology and entomology at the Government School of Agriculture, Potchefstroom. He became a member of the South African Association for the Advancement of Science in 1915 and a foundation member of the South African Biological Society in 1917.
Schlupp appears to have remained in South Africa until 1926. In collaboration with H. Terry he undertook tests of the effectiveness of different brands of lead arsenate in controlling Codling Moths. The results were reported in a progress report in the South African Fruit Grower (1919). He also produced several other publications: The principal orchard pests and how to control them (Johannesburg, 1919 or 1920, 29 pp.), based on an address to fruit growers; 'Mylabris beetles' (1920, Vol. 1(8), pp. 741-749) and 'The granivorous bird problem' (1922, Vol. 4, pp. 432-446) in the Journal of the Department of Agriculture of the Union of South Africa); and 'Cetonid beetles' (South African Fruit Grower, 1922).